Alios BioPharma, Inc. is a biotechnology company located in San Francisco, California that is developing novel medicines that treat diseases in virology by activating pathways in the innate immune system. Alios is pursuing the development of both protein and small molecule therapeutics, each addressing major commercial market opportunities.

Alios is discovering and developing novel antiviral agents based on three platform technologies including: small molecule activators of innate immunity antiviral pathways (RNase L activation), phosphate protected nucleotide prodrugs, and glycoprotein-engineering of interferons (Glycoferon). This complementary group of platform technologies has the potential to generate a number of distinct therapeutic products to treat a variety of serious viral infections such as chronic hepatitis B and C, HIV infection, respiratory viruses (e.g. pandemic influenza) and emerging viral diseases (e.g. SARS).

At Alios, our science is the key to our success, and to improving patients' quality of life. Our pipeline of developing novel compounds and investigative therapies reflects our commitment to bring innovative products to patients with unmet needs in the areas of virology.

Responsibilities

Scientist, Analytical Chemistry

The position will provide analytical and purification supports to our medicinal chemistry efforts. Responsibilities include maintaining LC-MS and HPLC, analyzing chemical and biochemical materials, and conducting preparative HPLC purification. Responsibility may also include operation and maintenance of NMR, based on candidate’s previous experience. The incumbent will provide a technical leadership in analytical chemistry.

Requirements

Ph.D. in analytical chemistry or organic chemistry with 2+ years of postdoctoral experience, or MS in chemistry with 5+ years of experience in industrial setting.

Prior experience in operating and maintaining HPLC and LC-MS is required.

Experience in analysis and purification of nucleotides is preferred, but not required.

Experience in maintaining NMR is a plus.

The incumbent is expected to be detail-oriented and capable of handling multiple tasks in the area of analytical chemistry and purification.