 |
 |
 |
 |
 |
 |
|
Scientist I/II, Nucleoside Chemistry
Scientist I/II, Nucleoside Chemistry Alios BioPharma, Inc. is a biotechnology company located in San Francisco, California that is developing novel medicines that treat diseases in virology by activating pathways in the innate immune system. Alios is pursuing the development of both protein and small molecule therapeutics, each addressing major commercial market opportunities. Alios is discovering and developing novel antiviral agents based on three platform technologies including: small molecule activators of innate immunity antiviral pathways (RNase L activation), phosphate protected nucleotide prodrugs, and glycoprotein-engineering of interferons (Glycoferon). This complementary group of platform technologies has the potential to generate a number of distinct therapeutic products to treat a variety of serious viral infections such as chronic hepatitis B and C, HIV infection, respiratory viruses (e.g. pandemic influenza) and emerging viral diseases (e.g. SARS). At Alios, our science is the key to our success, and to improving patients' quality of life. Our pipeline of developing novel compounds and investigative therapies reflects our commitment to bring innovative products to patients with unmet needs in the areas of virology. Responsibilities: This is a hands-on, nucleoside specific synthetic chemistry position. The person at this position is expected to independently conduct synthesis of new chemical entities, including design of efficient synthetic routes and chemical structure assignments by NMR and MS spectra. ONLY candidates with experience in synthesis of nucleosides and nucleotides will be considered. Requirements: Ph.D. in synthetic organic or medicinal chemistry with 2+ years of experience in synthesis of nucleosides and nucleotides. Strong publications record (including patents) and demonstrated ability solving challenging synthetic problems
Application Process |